Can GastroElm Plus Help Dogs With Protein Losing Enteropathy (PLE)?
Posted by Michael Peterson on
Great question! Here’s a detailed explanation of how GastroElm Plus can help with PLE (Protein-Losing Enteropathy) in dogs:
What is PLE?
Protein-Losing Enteropathy (PLE) is a condition where a dog’s gastrointestinal tract loses excessive protein into the intestines, often due to inflammation, ulcers, or other intestinal damage. This can lead to:
- Chronic diarrhea
- Weight loss despite eating well
- Swelling (edema or ascites) due to low blood protein levels
- Poor nutrient absorption
How GastroElm Plus Helps with PLE
1. Protects and Coats the Digestive Lining
GastroElm Plus forms a soothing gel-like coating when mixed with water. This coating helps protect and soothe the irritated or damaged intestinal lining, which is often a contributing factor in PLE. By providing this physical barrier, it helps:
- Reduce further irritation from food, stomach acid, and digestive enzymes.
- Give the gut a chance to heal.
2. Reduces Inflammation
PLE is often caused or worsened by chronic inflammation in the gut (like in IBD). The slippery elm bark and marshmallow root in GastroElm Plus both have natural anti-inflammatory properties that can calm inflamed tissues and help restore balance.
3. Supports Healing and Nutrient Absorption
When the gut lining is damaged, it struggles to absorb nutrients (including protein). By helping to protect and heal the gut wall, GastroElm Plus can gradually improve nutrient absorption, which can help slow or stop the excessive loss of protein into the intestines.
4. Helps with Diarrhea Control
PLE dogs often experience chronic diarrhea, which contributes to nutrient loss. GastroElm Plus can help firm up stools by soothing the gut lining and improving overall gut health, which can slow or stop diarrhea over time.
5. Supports Liver Function (Optional Benefit)
Since GastroElm Plus also contains milk thistle seed (depending on the formula), it offers liver support, which is beneficial for dogs who have secondary liver stress due to PLE or concurrent liver conditions.
When to Use GastroElm Plus for PLE
- If your dog has been diagnosed with PLE.
- If your dog has chronic diarrhea, especially if it's linked to inflammatory bowel disease (IBD) or intestinal inflammation.
- If your vet has recommended protecting the gut lining while other medications (like steroids or antibiotics) are being used.
Not a Cure — But a Valuable Tool
It’s important to note that GastroElm Plus does not cure PLE directly — PLE often requires a combination of diet changes, medications (like steroids or immunosuppressants), and supportive care. However, it can significantly improve comfort, support healing, and reduce symptoms, making it an excellent supportive supplement.
Colla3 May Also Be A Valuable Addition:
Colla3 contains:
- 50% German-manufactured bovine collagen (Collinstant), providing Type I & Type III collagen, and
- 50% hydrolyzed chicken sternum collagen (Kollagen II-XS), providing Type II collagen,
Let’s break this down specifically for dogs with PLE (Protein-Losing Enteropathy).
How Each Collagen Type Relates to PLE and Gut Health
Collagen Type | Main Benefits | Relevance for PLE |
---|---|---|
Type I (bovine) | Skin, connective tissue, bone, overall structural integrity | Helpful for general tissue repair and supporting the gut lining (less direct than Type III) |
Type III (bovine) | Found in intestinal walls, blood vessels, skin | Critical for gut lining repair, especially in inflammation-induced PLE (like from IBD) |
Type II (chicken sternum) | Cartilage, joints, some gut lining support | Primarily supports joint health, but some emerging evidence suggests it could support mucosal immunity in the gut, especially if immune dysregulation contributes to the PLE (like in IBD or immune-mediated enteropathies) |
Would Colla3 Be Beneficial for PLE?
✅ Yes — Colla3 could absolutely be beneficial for a dog with PLE, especially if the PLE is associated with conditions like IBD, lymphangiectasia, or intestinal inflammation/ulceration.
Here’s why:
-
Gut Lining Repair (Type I & III Collagen)
- Type III collagen is essential for the structural integrity of the gut wall, which is typically compromised in dogs with PLE.
- Type I collagen provides additional structural support, helping to reinforce connective tissues surrounding the intestines.
-
Support for Intestinal Barrier Function
- A healthier, more resilient gut lining can help reduce protein leakage into the intestines.
- By reinforcing the gut’s collagen matrix, it may help the intestines retain proteins better rather than losing them through damaged or inflamed tissue.
-
Potential Immunomodulation (Type II Collagen)
- Type II collagen (from chicken sternum) is often linked to joint health, but some research suggests oral tolerance effects — meaning it may help modulate inappropriate immune responses in the gut.
- This could be particularly helpful if your dog’s PLE is immune-mediated (like in some cases of IBD-driven PLE).
-
Synergy with GastroElm Plus
- GastroElm Plus provides immediate soothing, protection, and anti-inflammatory support.
- Colla3 provides the actual building blocks for long-term gut wall repair.
- Together, they can work as a short-term (soothing) and long-term (rebuilding) combo.
Specific Scenarios Where Colla3 May Shine
- PLE from IBD or chronic inflammation — excellent fit
- PLE with suspected "leaky gut" component — excellent fit
- PLE secondary to lymphoma or severe infections — may be supportive but not curative
- PLE from lymphangiectasia — indirect benefit (supports general gut health, but won't directly address lymphatic issues)
How to Use Colla3 for a PLE Dog
- Daily use — typically mixed into food
- Combine with other gut support tools (like low-fat, highly digestible diets, GastroElm Plus, omega-3s, etc.)
- Monitor over time — collagen works slowly, so give it at least 6-8 weeks to assess benefits.
Conclusion
✅ Colla3 could be highly beneficial as part of a comprehensive gut support protocol for a dog with PLE.
It won’t "cure" PLE on its own (since PLE is often secondary to a larger disease process), but it can:
- Support gut healing and resilience
- Help reduce chronic inflammation damage to the intestinal lining
- Potentially aid immune balance if immune dysfunction is part of the problem